Endobronchial benign nerve sheath tumour presenting with significant shortness of breath and haemoptysis. Issue 7 (16th July 2018)

• Record Type: Journal Article
• Authors: Roman, Marius; Burbidge, Oliver; McCulloch, Tom; Majewski, Andrzej
• Is Part Of: Oxford medical case reports. Volume 2018:Issue 7(2018)
• Publication Date: 2018-07-16
• Subjects: Clinical medicine -- Case studies -- Periodicals; 616.09
• DOI: 10.1093/omcr/omy033
• Languages: English
• ISSNs: 2053-8855

Abstract

Abstract: Peripheral nerve sheath tumours are rare within the thoracic cavity, with non-specific presentation. A 29-year-old patient presented with shortness of breath, cough, haemoptysis and recurrent chest infections. Suspicion of a primary lung carcinoma or a neuroendocrine tumour was raised following a CT and PET-CT. An endobronchial tumour suggested on histology a diagnosis of benign nerve sheath tumour, with positive staining for S100, CD56 and CD34. Following lung resection, the patient complained of fatigue and developed subcutaneous erythematous nodules on the anterior right chest, which raised the suspicion for a differential diagnosis of neurofibromatosis type I. The nodules resolved spontaneously within two weeks and the diagnosis of neurofibromatosis was ruled out on subsequent magnetic resonance imaging head and chest.