0280 Traumatic Childhood Experiences, Poor Sleep and Chronic Fatigue Syndrome among Adult Women. (27th April 2018)

• Record Type: Journal Article
• Authors: McWhorter, K L; Parks, C L; D'Aloisio, A A; Rojo-Wissar, D M; Sandler, D P; Jackson, C L
• Is Part Of: Sleep. Volume 41(2018)Supplement 1
• Page Start: A108
• Page End: A108
• Publication Date: 2018-04-27
• Subjects: Sleep -- Physiological aspects -- Periodicals; Sleep disorders -- Periodicals; Sommeil -- Aspect physiologique -- Périodiques; Sommeil, Troubles du -- Périodiques; Sleep disorders; Sleep -- Physiological aspects; Sleep -- physiological aspects; Sleep Wake Disorders; Psychophysiology; Electronic journals; Periodicals; 616.8498
• DOI: 10.1093/sleep/zsy061.279
• Languages: English
• ISSNs: 0161-8105

Abstract

Abstract: Introduction: Trauma experienced in early life is a potential risk factor for Chronic Fatigue Syndrome (CFS) in adulthood, which may be exacerbated by poor sleep. Methods: Our cross-sectional analysis included 45, 400 participants in the Sister Study - a large cohort of U.S. women enrolled from 2003 to 2009. Reports of traumatic childhood experiences (TCEs) included sexual, physical and psychological/emotional trauma along with natural disasters/adverse life events. CFS (n=743, 2%) was based on reports of a physician's diagnosis. Sleep parameters were defined as recommended vs. poor for sleep duration (short: <7 hours; recommended: ≥7 to <9 hours; long: ≥9 hours), time to fall asleep (≤30 minutes vs. >30 minutes), night awakenings (<3 times vs. ≥3 times per night) and napping frequency (<3 times vs. ≥3 times per week). We used log-binomial regression to estimate prevalence ratios (PRs) of CFS among women who reported TCEs vs. no TCEs, and considered interactions by measures of poor sleep. Models were adjusted for age, race/ethnicity and parental/guardian educational attainment. Results: TCEs were reported by 67% of women with CFS and 50% of women without CFS. Women with CFS were more likely than women without CFS to report short sleep (33% vs. 28%), taking >30 minutes to fall asleep (33% vs. 17%), frequent night awakenings (25% vs. 14%) and frequent napping (19% vs. 10%). Compared to women with no TCEs, those with any TCE had a 96% higher prevalence of CFS (PR=1.96 [95% confidence interval (CI): 1.68–2.29]). Women reporting sexual (PR=1.93 [95%CI:1.65–2.27]), physical (PR=2.50 [95%CI:2.07–3.01]) and psychological/emotional trauma (PR=1.72 [95%CI:1.49–1.99]) and natural disasters/adverse life events (PR=1.99 [95%CI:1.72–2.31]) also had a higher prevalence of CFS compared to women reporting no TCEs. The association between TCEs and CFS was stronger among women reporting any of these poor sleep characteristics than women reporting recommended sleep patterns and no TCEs. Conclusion: Suboptimal sleep patterns may modify the association between TCEs and CFS among adult women and may depend on type of TCE. Support (If Any): NIEHS, Z1AES103325-01.