533PDistinct clinico-pathological features of hypermutant colorectal cancers with POLE pathogenic mutations, Lynch syndrome and sporadic MSI analyzed over 1, 000 colorectal cancer patients. (23rd October 2018) - Nagasaka, T; Nyuya, A; Tanioka, H; Katata, Y; Yokota, M; Taniguchi, F; Kawai, T; Mori, Y; Shigeyasu, K; Okawaki, M; Yamamura, M; Umeda, Y; et al.