A case of a Müllerian cyst arising in the posterior mediastinum. Issue 11 (9th October 2018)

• Record Type: Journal Article
• Authors: Yasukawa, Motoaki; Uchiyama, Tomoko; Ohbayashi, Chiho; Kawaguchi, Takeshi; Kawai, Norikazu; Sawabata, Noriyoshi; Taniguchi, Shigeki
• Is Part Of: Oxford medical case reports. Volume 2018:Issue 11(2018)
• Publication Date: 2018-10-09
• Subjects: Clinical medicine -- Case studies -- Periodicals; 616.09
• DOI: 10.1093/omcr/omy080
• Languages: English
• ISSNs: 2053-8855

Abstract

Abstract: A mediastinal Müllerian cyst is composed of heterotopic cystic Müllerian tissue resembling structures of the fallopian tube. We herein report a case of a mediastinal Müllerian cyst discovered during a medical check-up of a 41-year-old woman. She had no symptoms but had been diagnosed with hyperprolactinemia at the age of 24 years, for which she received hormonal therapy for 3 years. Chest computed tomography demonstrated a 3-cm-diameter cystic tumor in front of the Th10 vertebra. Thoracic surgery was performed to remove the tumor. The tumor was a monolocular cyst covered with a thin capsule, and pathological examination showed a thin-walled cyst lined by ciliated or non-ciliated columnar cells resembling tubal epithelium. Immunohistochemical analysis showed positive expression for paired box gene 8 and estrogen and progesterone receptors. The pathological diagnosis was a Müllerian cyst. A Müllerian cyst should be always be considered in patients with a mediastinal cyst.