441POT-1096: A first-in-class immunoactivating small molecule that targets the thioredoxin reductase/thioredoxin axis causes strong tumor growth inhibition by downregulating intratumoral tregs in a humanized TNBC-PDX model. (23rd October 2018) - Orwar, O; Lowstedt, I; Andersson, K; Gannedahl, G; Willman, G; Davidsson, M; Stafford, W; Trkulja, C