422PFirst-in-human study of the monopolar spindle 1 (Mps1) kinase inhibitor BAY 1161909 in combination with paclitaxel in subjects with advanced malignancies. (23rd October 2018) - Lorusso, P; Chawla, S P; Bendell, J; Shields, A F; Shapiro, G; Rajagopalan, P; Cyris, C; Bruns, I; Mei, J; Souza, F; Rasco, D; Eder, J P; et al.