Quantitative and Qualitative EEG as a Prediction Tool for Outcome and Complications in Acute Stroke Patients. (March 2020)

• Record Type: Journal Article
• Authors: Doerrfuss, Jakob I.; Kilic, Tayfun; Ahmadi, Michael; Holtkamp, Martin; Weber, Joachim E.
• Is Part Of: Clinical EEG and neuroscience. Volume 51:Number 2(2020)
• Page Start: 121
• Page End: 129
• Publication Date: 2020-03
• Subjects: electroencephalogram (EEG) -- quantitative EEG -- stroke -- functional outcome -- cognitive decline -- epilepsy -- seizures; Electroencephalography -- Periodicals; Neurosciences -- Periodicals; 616.8047547
• DOI: 10.1177/1550059419875916
• Languages: English
• ISSNs: 1550-0594

Abstract

Currently, the relevance of EEG measurements in acute stroke patients is considered low in clinical practice. However, recent studies on the predictive value of EEG measurements after stroke for various outcomes may increase the role of EEG in patients with stroke. We aimed to review the current literature on the utility of EEG measurements after stroke as a tool to predict outcome and complications, focusing on studies in which the EEG measurement was performed in the acute phase after the event and in which long-term outcome measures were reported. In our literature review, we identified 4 different outcome measures (functional outcome, mortality, development of post-stroke cognitive decline, and development of post-stroke epilepsy) where studies on the utility of acute EEG measurements exist. There is a large body of evidence for the prediction of functional outcome, in which a multitude of associated quantitative and qualitative EEG parameters are described. In contrast, only few studies focus on mortality as outcome parameter. We found studies of high methodical quality on the prediction of post-stroke cognitive decline, though the number of patients in these studies often was small. The role of EEG as a prediction tool for seizures and epilepsy after stroke could increase after a recently published study, especially if its result can be incorporated into already existing post-stroke epilepsy prediction tools. In summary, EEG is useful for the prediction of functional outcome, mortality, development of post-stroke cognitive decline and epilepsy, even though there is a discrepancy between the large amount of studies on EEG in acute stroke patients and its underuse in clinical practice.