Refractory Pseudomonas Bacteremia in a 2-Year-Old Sterilized by Bacteriophage Therapy. (22nd July 2017)

• Record Type: Journal Article
• Authors: Duplessis, C; Biswas, B; Hanisch, B; Perkins, M; Henry, M; Quinones, J; Wolfe, D; Estrella, L; Hamilton, T
• Is Part Of: Journal of the Pediatric Infectious Diseases Society. Volume 7:Number 3(2018:Sep.)
• Page Start: 253
• Page End: 256
• Publication Date: 2017-07-22
• Subjects: bacteremia -- bacteriophage -- multidrug resistance -- Pseudomonas aeruginosa -- sepsis; Communicable diseases in children -- Periodicals; Children -- Diseases -- Periodicals; 618.929
• DOI: 10.1093/jpids/pix056
• Languages: English
• ISSNs: 2048-7193

Abstract

Abstract: Here, we report a complex case that involved a pediatric patient who experienced recalcitrant multidrug-resistant Pseudomonas aeruginosa infection complicated by bacteremia/sepsis; our antibacterial options were limited because of resistance, allergies, and suboptimal source control. A cocktail of 2 bacteriophages targeting the infectious organism introduced on 2 separate occasions sterilized the bacteremia.