Admission and mortality at the main neonatal intensive care unit in Guinea-Bissau. (13th July 2018)

• Record Type: Journal Article
• Authors: Pinstrup Joergensen, Anne Sofie; Bjerregaard-Andersen, Morten; Biering-Sørensen, Sofie; Byberg, Stine; Camala, Luis; Martins, Cesario; Rodrigues, Amabelia; Aaby, Peter; Stabell Benn, Christine
• Is Part Of: Transactions of the Royal Society of Tropical Medicine and Hygiene. Volume 112:Number 7(2018)
• Page Start: 335
• Page End: 341
• Publication Date: 2018-07-13
• Subjects: Africa -- incubator -- intensive care -- low-income setting -- neonatal mortality; Tropical medicine -- Periodicals; 616.9883
• DOI: 10.1093/trstmh/try061
• Languages: English
• ISSNs: 0035-9203

Abstract

Abstract: Background: The authors assessed the risk of admission and mortality at the main neonatal intensive care unit (NICU) at the National Hospital Simão Mendes (NHSM) in Guinea-Bissau. Methods: The Bandim Health Project (BHP) maintains a health and demographic surveillance system (HDSS) in the capital Bissau, including at the NHSM. Data from January 2008 to August 2013 was used to assess NICU incubator admissions and mortality. Results: The overall NICU admission rate was 4.8% (1575/33, 005); the lowest rate in 2012 (4.0% (214/5293)) and the highest rate in 2009 (6.0% (369/6134)). The overall mortality among admitted children was 19.6% (289/1476), declining from 26.7% (68/255) in 2008 to 13.0% (16/123) in 2013. Birth weight <1500 g (OR=353, (95% CI: 244–510) compared with normal birth weight 2500 g–4000 g), Apgar score≤3 (OR=13.2 (9.72–18.0) compared with Apgar score 7–10) and single motherhood (OR=1.44 (1.20–1.74)) were associated with NICU admission. Low Apgar score was a risk factor for NICU mortality (OR=6.21 (2.05–18.81)) and females (OR=0.55 (0.38–0.79) had a lower mortality than males. Conclusion: Approximately 5% of the hospital-born children were admitted to an incubator and among those almost 20% died, although mortality did decline. Male sex, very low birth weight and low Apgar score were strongly associated with NICU admissions and mortality.