Remission of type 2 diabetes and pleiotropic effects of long-term testosterone treatment for "late-onset" hypogonadism: A case report. (January 2019)

• Record Type: Journal Article
• Authors: Haider, Ahmad; Haider, Karim; Saad, Farid; Hanefeld, Markolf
• Is Part Of: SAGE open medical case reports. Volume 7(2019)
• Publication Date: 2019-01
• Subjects: Testosterone therapy -- type 2 diabetes -- "late-onset" hypogonadism -- obesity -- cardiometabolic risk factors; Clinical medicine -- Case studies -- Periodicals; 616.09
• DOI: 10.1177/2050313X18823454
• Languages: English
• ISSNs: 2050-313X

Abstract

For obese type 2 diabetes patients, weight reduction is one of the most important measures but fails in most cases. Testosterone deficiency can be the reason for such failure. This case presents a 57-year-old man who was referred to a urologist due to benign prostatic hyperplasia and erectile dysfunction. He had type 2 diabetes, was overweight, and had hypertension and dyslipidemia. The blood test revealed testosterone deficiency. Under testosterone therapy, the patient lost 10 kg; cardiometabolic parameters returned to normal and lower urinary tract symptoms disappeared; complete remission of diabetes was recorded. Overweight and obese patients with type 2 diabetes should be tested for hypogonadism and testosterone therapy, if indicated, be considered. These patients can considerably benefit from testosterone therapy in terms of sustainable weight loss and a clinically significant reduction of cardiometabolic risk factors including complete remission of diabetes.