Structural basis for the heme transfer reaction in heme uptake machinery from Corynebacteria. Issue 92 (31st October 2019)

• Record Type: Journal Article
• Authors: Muraki, Norifumi; Kitatsuji, Chihiro; Okamoto, Yasunori; Uchida, Takeshi; Ishimori, Koichiro; Aono, Shigetoshi
• Is Part Of: Chemical communications. Volume 55:Issue 92(2019)
• Page Start: 13864
• Page End: 13867
• Publication Date: 2019-10-31
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c9cc07369h
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : The CR domains in HtaA and HtaB are responsible for heme binding/transport in the heme-uptake machinery in Corynebacteria. Abstract : The crystal structures of the conserved region domains of HtaA and HtaB, which act as heme binding/transport proteins in the heme uptake machinery in Corynebacterium glutamicum, are determined for the first time. The molecular mechanism of heme transfer among these proteins is proposed based on the spectroscopic and structural analyses.