Thiopurines in Inflammatory Bowel Disease: New Findings and Perspectives. (25th December 2017)

• Record Type: Journal Article
• Authors: de Boer, Nanne K H; Peyrin-Biroulet, Laurent; Jharap, Bindia; Sanderson, Jeremy D; Meijer, Berrie; Atreya, Imke; Barclay, Murray L; Colombel, Jean-Frederic; Lopez, Anthony; Beaugerie, Laurent; Marinaki, Anthony M; van Bodegraven, Adriaan A; Neurath, Markus F
• Is Part Of: Journal of Crohn's and colitis. Volume 12:Number 5(2018:May)
• Page Start: 610
• Page End: 620
• Publication Date: 2017-12-25
• Subjects: Thiopurines -- azathioprine -- mercaptopurine -- thioguanine -- inflammatory bowel disease -- Crohn's disease -- ulcerative colitis -- therapeutic drug monitoring; Inflammatory bowel diseases -- Periodicals; 616.344005
• DOI: 10.1093/ecco-jcc/jjx181
• Languages: English
• ISSNs: 1873-9946

Abstract

Abstract: Thiopurines, available as azathioprine, mercaptopurine, and thioguanine, are immunomodulating agents primarily used to maintain corticosteroid-free remission in patients with inflammatory bowel disease. To provide a state-of-the-art overview of thiopurine treatment in inflammatory bowel disease, this clinical review critically summarises the available literature, as assessed by several experts in the field of thiopurine treatment and research in inflammatory bowel disease.