Bilateral Transient Myopia with Sulfasalazine Treatment. Issue 12 (June 2019)

• Record Type: Journal Article
• Authors: Paz, Tal; Rappoport, Daniel; Hilely, Assaf; Leiba, Hana
• Is Part Of: Clinical medicine insights. Issue 12(2019)
• Publication Date: 2019-06
• Subjects: drug-induced myopia -- acute myopia -- transient -- Sulfasalazine -- ciliary body edema; Clinical medicine -- Case studies -- Periodicals; Medicine; Clinical medicine; Electronic journals; Case Reports; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; Case studies; Periodicals; 616.09
• DOI: 10.1177/1179547619855388
• Languages: English
• ISSNs: 1179-5476

Abstract

Purpose: Several case reports of transient drug-induced myopia have been reported, mainly due to sulfa drugs. We present a case of a sudden and significant increase in myopia associated with initiation of Sulfasalazine for long-standing ulcerative colitis in an adult Caucasian female. Case report: Our patient presented to the emergency room with acute bilateral visual loss. Ocular examination was normal, except for myopia of −4 Diopters (D) in both eyes (BE). The patient was advised to stop the medication, and her vision improved within 4 days to best corrected visual acuity (BCVA) of 6/7.5 with a refractive correction of −0.75 D in her right eye (RE) and BCVA of 6/6 with a refractive correction of −0.50 D in her left eye (LE). Conclusion: To the best of our knowledge, this is the second reported case of transient Sulfasalazine-induced myopia.