A rare case of malignant meningitis from a likely bronchogenic melanoma primary cancer. Issue 1 (24th January 2019)

• Record Type: Journal Article
• Authors: Little, Jessica; Rajkumar, Christopher; Saleem, Waqar
• Is Part Of: Oxford medical case reports. Volume 2019:Issue 1(2019)
• Publication Date: 2019-01-24
• Subjects: Clinical medicine -- Case studies -- Periodicals; 616.09
• DOI: 10.1093/omcr/omy114
• Languages: English
• ISSNs: 2053-8855

Abstract

Abstract: Malignant meningitis is a rare condition with varied clinical presentations, often mimicking other neurological conditions. Here we report a rare case of malignant meningitis from primary bronchogenic melanoma. The patient initially presented with vomiting and headache. Over the next 12 days she developed rapidly progressive neurology: losing mental faculties, vision, hearing and limb power. Lumbar puncture results revealed malignant cells. Computer tomography of the chest found an endobronchial lesion which was later biopsied and histology revealed a melanoma. This condition is very rare and diagnosis was difficult. We discuss ideas to help expedite diagnosis and management of such cases in the future.