Transcatheter heart valve interventions: where are we? Where are we going?. (4th January 2019)

• Record Type: Journal Article
• Authors: Prendergast, Bernard D; Baumgartner, Helmut; Delgado, Victoria; Gérard, Olivier; Haude, Michael; Himmelmann, Anders; Iung, Bernard; Leafstedt, Matthew; Lennartz, Jasmine; Maisano, Francesco; Marinelli, Elena Andreassi; Modine, Thomas; Mueller, Markus; Redwood, Simon R; Rörick, Olaf; Sahyoun, Cherif; Saillant, Erika; Søndergaard, Lars; Thoenes, Martin; Thomitzek, Karen; Tschernich, Marion; Vahanian, Alec; Wendler, Olaf; Zemke, Evelyn Julia; Bax, Jeroen J
• Is Part Of: European heart journal. Volume 40:Number 5(2019)
• Page Start: 422
• Page End: 440
• Publication Date: 2019-01-04
• Subjects: Heart valve disease -- Transcatheter aortic valve replacement -- Aortic valve -- Mitral valve -- Tricuspid valve; Cardiology -- Periodicals; Heart -- Diseases -- Periodicals; 616.12005
• DOI: 10.1093/eurheartj/ehy668
• Languages: English
• ISSNs: 0195-668X

Abstract

Abstract: Transcatheter heart valve interventions have transformed the outcomes of patients with valvular heart disease (VHD) who are unfavourable candidates for surgery. Technological advances have allowed extension of these interventions to younger or lower risk patients and those with other forms of VHD and may in the future permit earlier treatment of VHD in less symptomatic patients or those with moderate disease. The balance of risks and benefits is likely to differ between lower and higher risk patients, and more evidence is needed to evaluate the net benefit of transcatheter technology in these groups. As academic researchers, clinicians, industry, and patient stakeholders collaborate to research these broader indications for transcatheter valve interventions, it is essential to address (i) device durability and deliverability, (ii) specific anatomical needs (e.g. bicuspid aortic valves, aortic regurgitation, mitral and tricuspid valve disease), (iii) operator training, and (iv) the reinforced importance of the multidisciplinary Heart Team.