Antifungal activity in the methanolic, aqueous and hexane extracts of Calligonum polygonoides. (January 2019)

• Record Type: Journal Article
• Authors: Ahmad, Saeed; Akram, Muhammad
• Is Part Of: International journal of immunopathology and pharmacology. Volume 33(2019)
• Publication Date: 2019-01
• Subjects: antifungal activity -- Aspergillus niger -- Calligonum polygonoides; Immunopathology -- Periodicals; Pharmacology -- Periodicals; Inflammation -- Periodicals; 615.1
• DOI: 10.1177/2058738418821275
• Languages: English
• ISSNs: 0394-6320

Abstract

Calligonum polygonoides is locally called as Phog which belongs to the Polygonaceae family. It is traditionally used as an antifungal. The methanolic extract, hexane extract, ethyl acetate extract and aqueous extract were screened against Candida albicans and Aspergillus niger in seven concentrations, that is, 1.8, 2.9, 6.5, 12.6, 25, 50 and 75 µg/mL/disc. Calligonum polygonoides showed significant activity against Candida albicans as the observed minimum inhibitory concentration (MIC) is 6.5 µg/mL for methanolic extract, 9.8 µg/mL for ethyl acetate extract, whereas aqueous and hexane extracts showed no activity. Calligonum polygonoides did not show any significant activity against Aspergillus niger.