Trisulfides over disulfides: highly selective synthetic strategies, anti-proliferative activities and sustained H2S release profiles. Issue 90 (24th October 2019)

• Record Type: Journal Article
• Authors: Bhattacherjee, Debojit; Sufian, Abu; Mahato, Sulendar K.; Begum, Samiyara; Banerjee, Kaustav; De, Sharmistha; Srivastava, Hemant Kumar; Bhabak, Krishna P.
• Is Part Of: Chemical communications. Volume 55:Issue 90(2019)
• Page Start: 13534
• Page End: 13537
• Publication Date: 2019-10-24
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c9cc05562b
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Highly selective synthesis of trisulfides over disulfides is demonstrated along with their potential as anti-proliferative agents and sustained donors of H2 S. Abstract : Temperature- and solvent-induced selective synthesis of trisulfides and disulfides is demonstrated. A remarkable selectivity was achieved using Na2 S as a sulfur-transfer agent under mild, greener, catalyst-free and additive-free conditions. This study reveals trisulfides as a better model than disulfides in general for a sustained release of H2 S and potent anti-cancer activities.