0788 Sleep Characteristics Of Children With Tourette Syndrome And Explosive Outbursts. (12th April 2019)

• Record Type: Journal Article
• Authors: Leclerc, Julie B; Chevrier, Élyse; Chicoine, Marjolaine; Godbout, Roger
• Is Part Of: Sleep. Volume 42(2019)Supplement 1
• Page Start: A316
• Page End: A317
• Publication Date: 2019-04-12
• Subjects: Sleep -- Physiological aspects -- Periodicals; Sleep disorders -- Periodicals; Sommeil -- Aspect physiologique -- Périodiques; Sommeil, Troubles du -- Périodiques; Sleep disorders; Sleep -- Physiological aspects; Sleep -- physiological aspects; Sleep Wake Disorders; Psychophysiology; Electronic journals; Periodicals; 616.8498
• DOI: 10.1093/sleep/zsz067.786
• Languages: English
• ISSNs: 0161-8105

Abstract

Abstract: Introduction: Tourette Syndrome (TS) is defined by motor and sound tics. Opposition and aggressive behaviors are common in children with TS, and some even experience explosive outbursts. These sudden and recurrent events are considered the worst symptoms by parents because of their severe interference with daily functioning. It is estimated that about 25% of children with TS will have sleep problems. Since inadequate sleep exacerbates behavioral symptoms of children with psychiatric disorders, we investigated whether poor sleep and explosive outbursts are association together in children with TS. Methods: Seven boys with TS (9.4±1.1 years old) and enrolled in a cognitive-behavioral program aiming at decreasing explosive outbursts were recruited. Sleep was recorded with actigraphy for 2 consecutive weeks prior to the intervention and parents filled a sleep diary during the same period as well as after the intervention. Both the mothers and the fathers filled the Children Sleep Habits Questionnaire (CSHQ) before and after the intervention. Explosive outbursts were scored from 1 (less severe) to 10 (more severe). Results: The average actigraphy data over 2 weeks for the 7 children was not atypical, including sleep latency (26.9 ± 4.0 min.), total sleep time (493.1 ± 19.5 min.) and sleep efficiency (90.8% ± 1.1%). Three out of the 7 participants experienced explosive outbursts during the actigraphy recording period, for a total of 8 events (mean severity score: 6.3 ± 0.9). There were no differences in actigraphy variables extracted from the nights preceding and those immediately following the explosive outbursts. During the pre-intervention period, mothers and fathers responded in similar ways to the CSHQ (total score 49.4 ± 2.9 vs 46.4 ± 1.7, respectively), but mothers reported more parasomnias (11.1±1.2 vs 9.6±1.3; p<0.01). All of the children exceeded the CSHQ clinical cut-off of 41. Post-intervention analyses are currently being analyzed. Conclusion: Children with TS display signs of sleep disorders according to CSHQ scores but not actigraphy. Explosive outbursts do not seem to be preceded nor followed by particular sleep patterns. Support (If Any): Institut universitaire en santé mentale de Montréal