0645 REM without Atonia In Combat Veterans With PTSD And Co-morbid OSA. (12th April 2019)

• Record Type: Journal Article
• Authors: Rizzo, Meagan M; Holley, Aaron B; Terry, Seth; Robertson, Brian; Collen, Jacob F
• Is Part Of: Sleep. Volume 42(2019)Supplement 1
• Page Start: A257
• Page End: A258
• Publication Date: 2019-04-12
• Subjects: Sleep -- Physiological aspects -- Periodicals; Sleep disorders -- Periodicals; Sommeil -- Aspect physiologique -- Périodiques; Sommeil, Troubles du -- Périodiques; Sleep disorders; Sleep -- Physiological aspects; Sleep -- physiological aspects; Sleep Wake Disorders; Psychophysiology; Electronic journals; Periodicals; 616.8498
• DOI: 10.1093/sleep/zsz067.643
• Languages: English
• ISSNs: 0161-8105

Abstract

Abstract: Introduction: Trauma Associated Sleep Disorder (TSD) may represent a distinct parasomnia induced by trauma exposure. A recent published series demonstrated varying degrees of REM without atone (RSWA, 13-37%). It is unclear if TSD has an overall pathologic increase in RSWA versus focal periods of RSWA associated with nightmares or disruptive nocturnal behavior (DNB). The purpose of this study is to describe the degree of RSWA in patients with PTSD+OSA who are at risk for TSD. Methods: Retrospective review of initial level 1 attended diagnostic video polysomnography (PSG) for 66 patients with combat related PTSD+OSA who were enrolled in a clinical trial measuring CPAP adherence. RSWA was scored in 3-second mini-epochs as having (or not having) "any" EMG activity according to the Sleep Innsbruck Barcelona group method. Results: Among 66 patients with PTSD+OSA, most were male (86%) with a mean age of 41.4±8.0 years and BMI of 28.6 vs 29.1 kg/m 2 . The median AHI was 18.8 events/hour with a baseline ESS (11.9±5.7 points) and ISI (17.6±5.0 points). During the diagnostic PSG 16 (57.1%) received either eszopiclone or zolpidem. On video PSG the presence of REM without atonia using the "any" EMG activity criteria ranged from 6.2-12.3% and no abnormal motor behaviors were observed. Conclusion: This is the first study to characterize the degree of RSWA among veterans with recently diagnosed PTSD+OSA. As the clinical characteristics and diagnostic criteria of Trauma Associated Sleep Disorder (TSD) are developed it will be important to take into consideration the normative values for RSWA in this unique, at risk patient population. Support (If Any): n/a