Synthesis of new water-soluble ionic liquids and their antibacterial profile against gram-positive and gram-negative bacteria. Issue 10 (October 2019)

• Record Type: Journal Article
• Authors: Duman, Ali Niyazi; Ozturk, Ismail; Tunçel, Ayça; Ocakoglu, Kasim; Colak, Suleyman Gokhan; Hoşgör-Limoncu, Mine; Yurt, Fatma
• Is Part Of: Heliyon. Volume 5:Issue 10(2019)
• Publication Date: 2019-10
• Subjects: Inorganic chemistry -- Organic chemistry -- Bacteria -- Microorganism -- Biofilms -- Antibacterial activity -- Imidazolium salt -- Ionic liquids -- Imidazolium cation -- Antibiofilm effect; Research -- Periodicals; Medical sciences -- Periodicals; Natural history -- Periodicals; Social sciences -- Periodicals; Earth sciences -- Periodicals; Physical sciences -- Periodicals; 507.2
• DOI: 10.1016/j.heliyon.2019.e02607
• Languages: English
• ISSNs: 2405-8440

Abstract

Abstract: A series of imidazolium bromide salts (NIM-Br 1a, 1b and 1c) bearing different lengths of alkyl chains were synthesized and their in vitro antibacterial activities were determined by measuring the minimum inhibitory concentration (MIC) values for Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Enterococcus faecalis . In addition, these imidazolium derivatives were also evaluated against biofilm produced by these bacterial strains. All compounds were found to be effective against Gram-positive and Gram-negative bacteria, and also more effective on the S. aureus biofilm production than the others. Abstract : Inorganic chemistry; Organic chemistry; Bacteria; Microorganism; Biofilms; Antibacterial activity; Imidazolium salt; Ionic liquids; Imidazolium cation; Antibiofilm effect