PVP‐co‐DMAEMA as Novel Polymeric Coating Material for Probiotic Supplements Delivery. Issue 21 (30th September 2019)

• Record Type: Journal Article
• Authors: D'Orazio, Giuseppe; De Giani, Alessandra; Zampolli, Jessica; Zeaiter, Zahraa; Di Gennaro, Patrizia; La Ferla, Barbara
• Is Part Of: Macromolecular chemistry and physics. Volume 220:Issue 21(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-09-30
• Subjects: microencapsulation -- pH responsiveness -- polymer coating -- probiotics; Polymers -- Periodicals; Polymerization -- Periodicals; Synthetic products -- Periodicals; Macromolecules -- Periodicals; 547.7
• DOI: 10.1002/macp.201900291
• Languages: English
• ISSNs: 1022-1352

Abstract

Abstract: The paper investigates the use of poly(1‐vinylpyrrolidone‐co‐2‐dimethylaminoethylmetacrilate) (PVP‐co‐DMAEMA) as a novel coating agent in the preparation of alginate‐based microcapsule for the supplement delivery of probiotics. Probiotic Lactobacillus plantarum is used to study the viability of the encapsulated bacterium when exposed to conditions simulating the gastrointestinal tract and industrial process. Results demonstrate that the PVP‐co‐DMAEMA polymer constitutes a pH‐responsive coating suitable for probiotic supplement delivery. Abstract : A novel coating agent, the poly(1‐vinylpyrrolidone‐co‐2‐dimethylaminoethylmetacrilate) (PVP‐co‐DMAEMA), is used to prepare the alginate‐based microcapsules for the supplement delivery of probiotics. The viability of the encapsulated probiotic Lactobacillus plantarum is evaluated simulating the gastrointestinal tract condition and the industrial process. The synthetic PVP‐co‐DMAEMA polymer is revealed to be a suitable pH‐responsive coating useful for probiotic delivery.