A full-spectrum-absorption from nickel sulphide nanoparticles for efficient NIR-II window photothermal therapy. Issue 42 (16th October 2019)

• Record Type: Journal Article
• Authors: Lei, Ziyu; Zhang, Wenlong; Li, Bo; Guan, Guoqiang; Huang, Xiaojuan; Peng, Xuan; Zou, Rujia; Hu, Junqing
• Is Part Of: Nanoscale. Volume 11:Issue 42(2019)
• Page Start: 20161
• Page End: 20170
• Publication Date: 2019-10-16
• Subjects: Nanoscience -- Periodicals; Nanotechnology -- Periodicals; 620.505
• DOI: 10.1039/c9nr04005f
• Languages: English
• ISSNs: 2040-3364

Abstract

Abstract : Ni9 S8 NPs with a full-spectrum-absorption could be used as a comparison platform to demonstrate the superiority of NIR-II ( i.e., 1064 nm) laser to NIR-I ( i.e., 808, 915, and 976 nm) laser, and irradiated by 1064 nm laser for efficient NIR-II photo-thermal therapy. Abstract : Near-infrared (NIR) light has been widely applied in the field of photothermal therapy (PTT). Recent advances in the light wavelength for efficient cancer PTT have gradually shifted from the first NIR (NIR-I) biowindow (700–1000 nm) to the second NIR (NIR-II) biowindow (1000–1350 nm) owing to its intrinsic deeper tissue penetration ability and a higher maximum permissible exposure (MPE) value. Herein, we have prepared nickel sulphide (Ni9 S8 ) nanoparticles (NPs) with a full-spectrum-absorption (400 nm–1100 nm) in the NIR region. By a fair comparison, it is found that the PTT using the NPs upon irradiation from an NIR-II ( i.e., 1064 nm) laser is more efficient than that from an NIR-I ( i.e., 808, 915, and 976 nm) laser. The large mass extinction coefficient value (22.18 L g −1 cm −1 ) and high photothermal conversion efficiency (46%) at 1064 nm make these NPs promising candidates for NIR-II photo-thermal therapy. This study will benefit future exploration and optimization of nickel-based photoabsorbers utilizing NIR-II light for photothermal applications.