Are Many Patients Diagnosed With Healthcare-associated Clostridioides difficile Infections Colonized With the Infecting Strain on Admission?. (11th March 2019)

• Record Type: Journal Article
• Authors: Gonzalez-Orta, Melany; Saldana, Carlos; Ng-Wong, Yilen; Cadnum, Jennifer; Jencson, Annette; Jinadatha, Chetan; Donskey, Curtis J
• Is Part Of: Clinical infectious diseases. Volume 69:Number 10(2019)
• Page Start: 1801
• Page End: 1804
• Publication Date: 2019-03-11
• Subjects: Clostridioides difficile -- colonization -- healthcare-associated -- whole genome sequencing -- infection control; Communicable diseases -- Periodicals; 616.905
• DOI: 10.1093/cid/ciz189
• Languages: English
• ISSNs: 1058-4838

Abstract

Abstract: In a cohort of 480 patients admitted to an acute care hospital, 68 (14%) had positive perirectal cultures for toxigenic Clostridioides difficile on admission. Of the 11 patients (2%) diagnosed with healthcare-associated C. difficile infections, 3 (27%) had genetically related admission and infection isolates, based on whole-genome sequencing.