Axially chiral N, N′‐dioxides ethers for catalysis in enantioselective allylation of aldehydes. Issue 11 (28th August 2019) - Wu, Shijie
Abstract: A series of axially chiral ethers synthesized from biscarboline N, N ′‐dioxides, ( S )‐1a to ( S )‐1n, was investigated in enantioselectivity addition reactions of allyltrichlorosilane with a series of substituted aldehydes, including bulky substituted aldehydes. High enantioselectivities (up to 96%ee) were achieved using the catalyst ( S )‐1k at 1 mol % loading. Abstract :