Early triple negative breast cancer: Are we getting better outcomes? A retrospective analysis from a single institution. Issue 6 (16th July 2019)

• Record Type: Journal Article
• Authors: Barchiesi, Giacomo; McCartney, Amelia; Biagioni, Chiara; Siclari, Olimpia; Rossi, Lorenzo; Pestrin, Marta; Di Leo, Angelo; Biganzoli, Laura
• Is Part Of: Breast journal. Volume 25:Issue 6(2019)
• Page Start: 1225
• Page End: 1229
• Publication Date: 2019-07-16
• Subjects: breast cancer -- elderly -- outcome -- prognosis -- triple negative; Breast -- Diseases -- Periodicals; Breast -- Cancer -- Periodicals; 618.19
• DOI: 10.1111/tbj.13437
• Languages: English
• ISSNs: 1075-122X

Abstract

Abstract: Overall survival (OS), disease‐free survival (DFS), and distant recurrence‐free interval (DRFI) were evaluated from 169 patients diagnosed with early triple negative breast cancer. Overall, 5 and 10 years OS, DFS, and DRFI were 77% and 65%; 60% and 46%; and 74% and 73%, respectively. Forty‐seven patients did not receive chemotherapy. A separate analysis was performed excluding those patients. In this subgroup, 5‐ and 10‐year OS, DFS, and DRFI were 86% and 77%; 68% and 54%, 77% both at 5 and 10 years. Prognosis is better than previously described; adjuvant chemotherapy should be offered to fit elderly patients if clinically warranted.