Postoperative stress and pain response applying fast-track protocol in patients undergoing hepatectomy. Issue 11 (November 2019)

• Record Type: Journal Article
• Authors: Kapritsou, Maria; Konstantinou, Evangelos A; Korkolis, Dimitris P; Kalafati, Maria; Kaklamanos, Ioannis; Giannakopoulou, Margarita
• Is Part Of: Journal of perioperative practice. Volume 29:Issue 11(2019)
• Page Start: 368
• Page End: 377
• Publication Date: 2019-11
• Subjects: Fast-track after liver resection -- Stress response -- Surgery trauma -- Enhanced recovery program after liver resection -- Pain response; Operating room nursing -- Periodicals; 617.9192
• DOI: 10.1177/1750458918812293
• Languages: English
• ISSNs: 2515-7949

Abstract

Aim: To assess the clinical parameters and compare the stress and pain response between fast-track recovery protocol and conventional treatment in patients undergoing major liver resection. Methods: Eighty-eight patients suffering from malignant liver tumours were surgically treated from May 2012 to March 2015. After randomisation, they were prospectively divided into two groups: group fast-track patients (n = 46) and group conventional treatment patients (n = 42). Demographic and clinical data were collected and patients were assessed with pain scale (behavioural observation scale and visual analog scale), while depression levels were evaluated with Zung self-rating depression scale and three Numeric Analog Scale self-reported questions. Peripheral blood samples were collected at time points: T1 on the admission day, T2 on the day of surgery and T3 on the day of discharge examining serum levels of adrenocorticotropic hormone and cortisol. Conclusion: Fast-track recovery protocols seem to be associated with improvement in several clinical parameters, without compromising, biologic or emotional stress in patients undergoing major liver resection.