Follicular Dendritic Cell Sarcoma or Not? A Series of 5 Diagnostically Challenging Cases. (May 2019)

• Record Type: Journal Article
• Authors: Lopez-Hisijos, Nicolas; Omman, Reeba; Pambuccian, Stefan; Mirza, Kamran
• Is Part Of: Clinical medicine insights. Oncology. Volume 13(2019)
• Publication Date: 2019-05
• Subjects: FDCS -- follicular dendritic cell sarcoma -- pitfalls in diagnosis -- review -- tumors of the accessory immune system; Oncology -- Periodicals; 616.994005
• DOI: 10.1177/1179554919844531
• Languages: English
• ISSNs: 1179-5549

Abstract

Imperfect or unusual presentation, morphology, or immunophenotype can make the diagnosis of follicular dendritic cell sarcoma (FDCS) very challenging. To illustrate this, we present 5 unique cases from the archives of our tertiary care academic medical center that presented a diagnostic challenge wherein FDCS was the top differential diagnostic possibility. The workup of these cases, including multiple expert consultations, highlights the importance of avoiding specific pitfalls in the diagnosis of FDCS.