Decreased capillary density in renal cell carcinoma: Evidence from a case report with micro-computerized tomography. Issue 36 (September 2019)

• Record Type: Journal Article
• Authors: Lin, Tzu-Chun; Chen, Huey-Yi; Yang, You-Rong; Liu, Po-Len; Chen, Yung-Hsiang; Chen, Wen-Chi
• Other Names: NA. section editor.
• Is Part Of: Medicine. Volume 98:Issue 36(2019)
• Publication Date: 2019-09
• Subjects: capillary distribution -- micro-computerized tomography -- renal cell carcinoma; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Geneeskunde; Medicine; Periodicals; Periodicals; 610.5
• DOI: 10.1097/MD.0000000000016910
• Languages: English
• ISSNs: 0025-7974

Abstract

Abstract: Rationale: Conventional computerized tomography (CT) examination can differentiate renal cortical tumor from urothelial carcinoma on the basis of the highly contrast-enhanced vessels in renal cortical tumors. However, the capillary distribution of renal cell carcinoma (RCC) has been under-investigated. Here, we present a micro-CT image of tumor tissue in a patient with RCC. Patient concerns: The patient was a 72-year-old woman with a past history of diabetes mellitus and hypertension. She did not have tumor-related symptoms. Diagnosis and interventions: The tumor was diagnosed using abdominal CT during her yearly routine health check. After radical nephrectomy, the tumor was subjected to pathological examination and micro-CT imaging. Pathological analysis confirmed a clear cell renal carcinoma. The capillary distribution of the tumor was significantly lesser than that of the normal cortex on micro-CT image. Lessons: Microvessels of RCC can be detected by micro-CT. We also found that the distribution of microvessels was uneven and lower than that in the normal cortex in this case. For a more general diagnosis, more micro-CT images of RCC tumors are needed. Abstract : Supplemental Digital Content is available in the text