Simple and robust polymer-based sensor for rapid cancer detection using serum. Issue 76 (6th September 2019)

• Record Type: Journal Article
• Authors: Le, Ngoc D. B.; Singla, Arvind K.; Geng, Yingying; Han, Jinsong; Seehafer, Kai; Prakash, Gyan; Moyano, Daniel F.; Downey, Charlene M.; Monument, Michael J.; Itani, Doha; Bunz, Uwe H. F.; Jirik, Frank R.; Rotello, Vincent M.
• Is Part Of: Chemical communications. Volume 55:Issue 76(2019)
• Page Start: 11458
• Page End: 11461
• Publication Date: 2019-09-06
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c9cc04854e
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Rapid detection of cancer using a simple FRET-based polymer sensor. Abstract : We report a polymer-based sensor that rapidly detects cancer based on changes in serum protein levels. Using three ratiometric fluorescence outputs, this simple system identifies early stage and metastatic lung cancer with a high level of accuracy exceeding many biomarker-based assays, making it an attractive strategy for point-of-care testing.