Pulmonary Infections Caused by Emerging Pathogenic Species of Nocardia. (1st October 2019)

• Record Type: Journal Article
• Authors: Manoharan, Harish; Selvarajan, Sribal; Sridharan, K. S.; Sekar, Uma
• Other Names: Bush Larry M. Academic Editor.
• Is Part Of: Case reports in infectious diseases. Volume 2019(2019)
• Publication Date: 2019-10-01
• Subjects: Communicable diseases -- Periodicals; Communicable diseases -- Case studies -- Periodicals; Communicable Diseases; Infectious Disease Medicine; Communicable diseases; Electronic journals; Periodicals; Case studies; Periodicals; 616.9
• DOI: 10.1155/2019/5184386
• Languages: English
• ISSNs: 2090-6625

Abstract

Abstract : Pulmonary infections are the most common clinical manifestations of Nocardia species. There is an increase in cases of nocardial infections occurring worldwide attributable to the increase in the immunosuppressed population. The availability of molecular methods has aided the detection of more number of cases as well as unusual species. Still, it remains one of the most underdiagnosed pathogens. Recognition of drug resistance in this organism has now mandated early and precise identification with speciation for effective treatment and management. Nocardial species identity can predict antimicrobial susceptibility and guide clinical management. Here, we report two cases of pulmonary nocardiosis caused by unusual species of Nocardia, namely, N. cyriacigeorgica and N. beijingensis identified by 16S rRNA gene-based sequencing. These cases are being reported for their rarity.