Host blood-meal source has a strong impact on gut microbiota of Aedes aegypti. Issue 1 (24th October 2018)

• Record Type: Journal Article
• Authors: Muturi, Ephantus J; Dunlap, Christopher; Ramirez, Jose L; Rooney, Alejandro P; Kim, Chang-Hyun
• Is Part Of: FEMS microbiology ecology. Volume 95:Issue 1(2019)
• Publication Date: 2018-10-24
• Subjects: Ae. aegypti -- gut microbiota -- MiSeq sequencing -- host blood-meal source; Microbial ecology -- Periodicals; Microbiology -- Periodicals; 579.17
• DOI: 10.1093/femsec/fiy213
• Languages: English
• ISSNs: 0168-6496

Abstract

Abstract: Gut microbial communities of mosquitoes can influence vector susceptibility to pathogens, yet the factors that govern their composition remain poorly understood. We investigated the impact of host blood-meal source on gut microbiota of Aedes aegypti L. Adult mosquitoes were fed on human, rabbit or chicken blood and their gut microbiota compared to those of sugar-fed and newly emerged adults. Microbial diversity was significantly reduced in blood-fed and sugar-fed mosquitoes but was restored to the levels of newly emerged adults at 7-days post-blood meal. Microbial composition was strongly influenced by host blood-meal source. Leucobacter spp., Chryseobacterium spp., Elizabethkingia spp. and Serratia spp. were characteristic of newly emerged adults and adults fed on chicken, rabbit and human blood, respectively. Sugar-fed mosquitoes had higher abundance of Pseudomonas spp. and unclassified Acetobacteraceae. Shifts in gut microbial communities in response to host blood-meal source may fundamentally impact pathogen transmission given the well-documented link between specific bacterial taxa and vector susceptibility to a variety of mosquito-borne pathogens and may be a key determinant of individual and population variation in vector competence. Abstract : Gut bacterial communities of Aedes aegypti shift in response to host blood-meal source.