Complement 5a Receptor Polymorphisms Are Associated With Panton-Valentine Leukocidin–positive Staphylococcus aureus Colonization in African Pygmies. (6th September 2018)

• Record Type: Journal Article
• Authors: Schaumburg, Frieder; Witten, Anika; Flamen, Arnaud; Stoll, Monika; Alabi, Abraham S; Kremsner, Peter G; Löffler, Bettina; Zipfel, Peter F; Velavan, Thirumalaisamy P; Peters, Georg
• Is Part Of: Clinical infectious diseases. Volume 68:Number 5(2019)
• Page Start: 854
• Page End: 856
• Publication Date: 2018-09-06
• Subjects: Staphylococcus aureus -- complement C5a -- receptor -- Panton-Valentine leukocidin -- polymorphism; Communicable diseases -- Periodicals; 616.905
• DOI: 10.1093/cid/ciy666
• Languages: English
• ISSNs: 1058-4838

Abstract

Abstract: Panton-Valentine leukocidin (PVL) is common in African Staphylococcus aureus and can be associated with skin and soft tissue infection. PVL-positive S. aureus colonization is associated with a variant of complement receptor 5a, the cellular target of the lukS PVL subunit.