Quality of life after coronary bypass: a multicentre study of routinely collected health data in the Netherlands. (15th March 2019)

• Record Type: Journal Article
• Authors: Blokzijl, Fredrike; Houterman, Saskia; van Straten, Bart H M; Daeter, Edgar; Brandon Bravo Bruinsma, George J; Dieperink, Willem; Reneman, Michiel F; Keus, Frederik; van der Horst, Iwan C C; Mariani, Massimo A
• Is Part Of: European journal of cardio-thoracic surgery. Volume 56:Number 3(2019)
• Page Start: 526
• Page End: 533
• Publication Date: 2019-03-15
• Subjects: Cardiac surgery -- Coronary artery bypass grafting -- Quality of life; Heart -- Surgery -- Periodicals; Chest -- Surgery -- Periodicals; 617.54
• DOI: 10.1093/ejcts/ezz051
• Languages: English
• ISSNs: 1010-7940

Abstract

Abstract: OBJECTIVES: In this study, our aim was to explore how coronary artery bypass grafting affects quality of life, and how this varies with age, particularly with patients at risk of deterioration. METHODS: In a retrospective, multicentre cohort study, patients with isolated coronary artery bypass grafting and electively operated between January 2011 and January 2015 with pre- and postoperative quality-of-life data were included. Patients were classified into 3 age groups: <65, 65–79 and ≥80 years. Quality of life was measured up to 1-year follow-up using the Short Form-12 or the Short Form-36 health survey. A multivariable, linear regression analysis, with an adjustment for confounders, was used to evaluate the association between age and quality of life. RESULTS: A total of 2606 patients were included in this study. Upon one-year of follow-up, the mean physical health of patients increased from 54 at baseline to 68, and mental health increased from 60 to 67. We observed decreased mental health in 20% of patients aged <65 years, 20% of patients aged 65–79 years and 29% of patients aged ≥80 years ( P = 0.039). In this study, age was not associated with a lower physical or mental component score ( P = 0.054 and P = 0.13, respectively). Independent risk factors for a decrease in quality of life consist of a better physical and mental score at baseline ( P < 0.001) and a reduced left ventricular function ( P < 0.001). CONCLUSIONS: Most patients experience a relevant increase in physical and mental quality of life, but a proportion of patients aged ≥80 years undergo significant deterioration in mental health.