Fistuloates A–C: New antioxidative aromatic compounds isolated from Cassia fistula. Issue 11 (November 2019)

• Record Type: Journal Article
• Authors: Aftab, Zahida; Afzal, Masood; Bushra, ; Khan, Hidayatullah; Badshah, Syed; Khan, Dilfaraz; Ullah, Hamid; Khan, Shafiullah
• Is Part Of: Journal of chemical research. Volume 43:Issue 11/12(2019)
• Page Start: 516
• Page End: 521
• Publication Date: 2019-11
• Subjects: antioxidant activity -- C. fistula -- characterization -- ethyl acetate fraction -- fistuloates A–C; Chemistry -- Research -- Periodicals; Chemistry -- Periodicals; 540.5
• DOI: 10.1177/1747519819875052
• Languages: English
• ISSNs: 1747-5198

Abstract

Three new aromatic compounds named fistuloates:A (3-butyl-6-ethylnonyl-3-(1-phenylethyl) benzoate), B (3-(6- tert -butyl-1-ethoxy-5-ethyl-4-methylnonyl)-5-ethylbenzoic acid isobutyl ester) andC (4, 5-diethoxy-2-propylbenzoic acid 7-(6-pentyltetrahydropyran-2-yl)-heptyl ester) were isolated from the ethyl acetate soluble fraction of Cassia fistula Linn. The structural formulae of the isolated compoundsA–C were established through interpretation of their spectral data. CompoundsA–C exhibited significant antioxidant properties in 2, 2-diphenyl-1-picrylhydrazyl, 2, 2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) and superoxide anion radical scavenging assays that signifies that C. fistula carries potential anti-oxidant constituents and may assist to cure diseases associated with oxidative stress and others.