Dynamics of Breast Cancer under Different Rates of Chemoradiotherapy. (11th September 2019)

• Record Type: Journal Article
• Authors: Mkango, Sara B.; Shaban, Nyimvua; Mureithi, Eunice; Ngoma, Twalib
• Other Names: Karaman Rafik Academic Editor.
• Is Part Of: Computational and mathematical methods in medicine. Volume 2019(2019)
• Publication Date: 2019-09-11
• Subjects: Medicine -- Computer simulation -- Periodicals; Medicine -- Mathematical models -- Periodicals; 610.11
• DOI: 10.1155/2019/5216346
• Languages: English
• ISSNs: 1748-670X

Abstract

Abstract : A type of cancer which originates from the breast tissue is referred to as breast cancer. Globally, it is the most common cause of death in women. Treatments such as radiotherapy, chemotherapy, hormone therapy, immunotherapy, and gene therapy are the main strategies in the fight against breast cancer. The present study aims at investigating the effects of the combined radiotherapy and chemotherapy as a way to treat breast cancer, and different treatment approaches are incorporated into the model. Also, the model is fitted to data on patients with breast cancer in Tanzania. We determine new treatment strategies, and finally, we show that when sufficient amount of chemotherapy and radiotherapy with a low decay rate is used, the drug will be significantly more effective in combating the disease while health cells remain above the threshold.