Actin dynamics in host–pathogen interaction. Issue 22 (5th July 2018)

• Record Type: Journal Article
• Authors: Stradal, Theresia E. B.; Schelhaas, Mario
• Is Part Of: FEBS letters. Volume 592:Issue 22(2018)
• Page Start: 3658
• Page End: 3669
• Publication Date: 2018-07-05
• Subjects: actin dynamics -- bacterial invasion -- host–pathogen interaction -- viral entry -- virulence factors; Biochemistry -- Periodicals; Biophysics -- Periodicals; Molecular biology -- Periodicals; Biochimie -- Périodiques; Biochemistry; Biophysics; Molecular biology; Periodicals; 572.05
• DOI: 10.1002/1873-3468.13173
• Languages: English
• ISSNs: 0014-5793

Abstract

Abstract : The actin cytoskeleton and Rho GTPase signaling to actin assembly are prime targets of bacterial and viral pathogens, simply because actin is involved in all motile and membrane remodeling processes, such as phagocytosis, macropinocytosis, endocytosis, exocytosis, vesicular trafficking and membrane fusion events, motility, and last but not least, autophagy. This article aims at providing an overview of the most prominent pathogen‐induced or ‐hijacked actin structures, and an outlook on how future research might uncover additional, equally sophisticated interactions. Abstract :