Community matters: GxE interactions predicting childhood aggression and violent behavior. (March 2019)

• Record Type: Journal Article
• Authors: Sattler, Leslie J.; Thomas, Kristie A.; Vaughn, Michael G.; Almeida, Joanna; White, Lori A.; Waldman, Marcus R.
• Is Part Of: Journal of criminal justice. Number 61(2019)
• Page Start: 58
• Page End: 71
• Publication Date: 2019-03
• Subjects: Aggression -- Violent behavior -- Children -- Community level factors -- Gene-environment; Criminal justice, Administration of -- Periodicals; Justice pénale -- Administration -- Périodiques; 364.05
• DOI: 10.1016/j.jcrimjus.2019.03.002
• Languages: English
• ISSNs: 0047-2352

Abstract

Abstract: Purpose: Aggression in childhood is a common precursor to youth violence, yet few studies have examined the extent to which genetic and environmental factors interact (GxE) to influence aggression by male and female children.This secondary analysis of data from the Fragile Families and Child Wellbeing Study examined GxE interactions between two composites of genetic polymorphisms and community-level factors on childhood aggression and violent behavior. Methods: The analytic sample consisted of preadolescent children of single mothers (Year 3, n = 2102; Year 5, n = 2065; Year 9, n = 2007). Analysis included multiple regression and tests of differential susceptibility using simple slopes and regions of significance. Results: Findings indicate that low levels of neighborhood social control and community stability interacted with genotypes to predict childhood aggression and violent behavior at age 9. Moreover, girls who possessed specific dopamine and serotonin polymorphisms were differentially susceptible to the level of neighborhood social control. Conclusions: Findings underscore the need for interventions that work to strengthen communities' social control and residential stability as a way to reduce children's violence and improve their outcomes. Highlights: GxE with social control predicted childhood aggression and violent behavior. GxE with low levels of social control at age 3 predicted aggression for boys and girls. Girls were differentially susceptible to GxE with social control at age three. GxE with community instability predicted childhood aggression and violent behavior for boys. High levels of community instability predicted aggression for boys.