Percutaneous Endoscopic Transgastric Jejunostomy (PEG‐J) Tube Placement for Levodopa‐Carbidopa Intrajejunal Gel Therapy in the Interventional Radiology Suite: A Long‐term Follow‐up. Issue 2 (3rd January 2018)

• Record Type: Journal Article
• Authors: Saddi, Maria Valeria; Sarchioto, Marianna; Serra, Giulia; Murgia, Daniela; Ricchi, Valeria; Melis, Marta; Arca, Roberta; Carreras, Pierpaolo; Sitzia, Loredana; Zedda, Sandro; Dui, Giovanni; Rossi, Rosario; Ticca, Anna; Melis, Maurizio; Cossu, Giovanni
• Is Part Of: Movement disorders clinical practice. Volume 5:Issue 2(2018)
• Page Start: 191
• Page End: 194
• Publication Date: 2018-01-03
• Subjects: endoscopic gastrojejunostomy -- levodopa/carbidopa intestinal gel -- Parkinson's disease -- percutaneous radiologic gastrojejunostomy; Movement Disorders; Movement disorders -- Periodicals; Movement disorders; Periodicals; Periodicals; 616
• DOI: 10.1002/mdc3.12569
• Languages: English
• ISSNs: 2330-1619

Abstract

Abstract: Background: Percutaneous endoscopic gastrojejunostomy (PEG) and radiologically inserted gastrojejunostomy (RIG) are both safe and effective techniques for gastrojejunal tube placement. The authors compared these 2 procedures in patients with advanced Parkinson's disease (PD) who required the continuous intrajejunal delivery of a levodopa/carbidopa gel suspension (LCIG). Methods: Outcomes were retrospectively collated from 30 PEG and 12 RIG procedures performed at 2 centers in patients with advanced PD for the delivery of LCIG. Results: Baseline clinical characteristics, incidence of early severe adverse events, late major complications, dropout, and the mean time‐lapse of tube replacements were comparable in the PEG and RIG groups. Conclusion: The current results suggest that, in patients with PD, the RIG technique is as safe and effective as the endoscopic procedure, and it can be considered a valid option for patients who require LCIG when the endoscopic procedure is not available or unfeasible.