Visible‐Light‐Triggered, Metal‐ and Photocatalyst‐Free Acylation of N‐Heterocycles. Issue 21 (13th September 2018)

• Record Type: Journal Article
• Authors: Guillemard, Lucas; Colobert, Françoise; Wencel‐Delord, Joanna
• Is Part Of: Advanced synthesis & catalysis. Volume 360:Issue 21(2018)
• Page Start: 4184
• Page End: 4190
• Publication Date: 2018-09-13
• Subjects: acylation -- N-heterocycles -- visible-light -- EDA complex -- C−H functionalization -- photoactivation -- photocatalyst-free; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201800692
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: A photoinduced acylation of N ‐heterocycles is explored. This visible‐light triggered reaction occurs not only under extremely mild reaction conditions, but also does not require the presence of a photosensitizer. The mechanistic studies suggest formation of EDA complexes prompt to harness the energy from visible‐light. Compatibility with a large panel of α‐keto acids as acyl precursors and an array of N ‐heterocycles clearly showcase the synthetic potential of this handy and green acylation protocol. Abstract :