3D simulation of a viscous flow past a compliant model of arteriovenous-graft annastomosis. (15th March 2019)

• Record Type: Journal Article
• Authors: Bai, Zengding; Zhu, Luoding
• Is Part Of: Computers & fluids. Volume 181(2019)
• Page Start: 403
• Page End: 415
• Publication Date: 2019-03-15
• Subjects: Arteriovenous graft -- Blood flow -- Hemodialysis -- Fluid-structure interaction -- Immersed boundary method -- Lattice Boltzmann method -- Wall shear stress; Fluid dynamics -- Data processing -- Periodicals; 532.050285
• DOI: 10.1016/j.compfluid.2019.02.006
• Languages: English
• ISSNs: 0045-7930

Abstract

Abstract: Hemodialysis is a common treatment for end-stage renal-disease patients to manage their renal failure while awaiting kidney transplant. Arteriovenous graft (AVG) is a major vascular access for hemodialysis but often fails due to the thrombosis near the vein-graft anastomosis. Almost all of the existing computational studies involving AVG assume that the vein and graft are rigid. As a first step to include vein/graft flexibility, we consider an ideal vein-AVG anastomosis model and apply the lattice Boltzmann-immersed boundary (LB-IB) framework for fluid-structure-interaction. The framework is extended to the case of non-uniform Lagrangian mesh for complex structure. After verification and validation of the numerical method and its implementation, many simulations are performed to simulate a viscous incompressible flow past the anastomosis model under pulsatile flow condition using various levels of vein elasticity. Our simulation results indicate that vein compliance may lessen flow disturbance and a more compliant vein experiences less wall shear stress (WSS).