A Single‐Wavelength‐Emitting Ratiometric Probe Based on Phototriggered Fluorescence Switching of Graphene Quantum Dots. Issue 42 (3rd September 2014)

• Record Type: Journal Article
• Authors: Qu, Zhi‐bei; Zhang, Min; Zhou, Tianshu; Shi, Guoyue
• Is Part Of: Chemistry. Volume 20:Issue 42(2014)
• Page Start: 13777
• Page End: 13782
• Publication Date: 2014-09-03
• Subjects: analytical methods -- fluorescent probes -- graphene -- iron -- quantum dots; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201404160
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract: Ratiometric fluorescent probes are of great importance in research, because a built‐in correction for environmental effects can be provided to reduce background interference. However, the traditional ratiometric fluorescent probes require two luminescent materials with different emission bands. Herein a novel ratiometric probe based on a single‐wavelength‐emitting material is reported. The probe works by regulating the luminescent property of graphene quantum dots with UV illumination as activator. The ratiometric sensor shows high sensitivity and specificity for iron ions. Moreover, the ratiometric sensor was successfully employed to monitor ferritin levels in Sprague Dawley rats with chemical‐induced acute liver damage. The proposed single‐wavelength ratiometric fluorescent probe may greatly broaden the applicability of ratiometric sensors in diagnostic devices, medical applications, and analytical chemistry. Abstract : A new ratiometric strategy : A new type of ratiometric probe based on graphene quantum dots (GQDs) emitting single‐wavelength fluorescence was developed for the sensitive and selective determination of iron ions. The analytical method is based on the different responses of the GQDs to iron ions before and after UV irradiation (see figure; ROS: reactive oxygen species).