Management of patients with colorectal liver metastasis in eleven questions and answers. Issue 12 (1st December 2016)

• Record Type: Journal Article
• Authors: Andres, Axel; Majno, Pietro; Terraz, Sylvain; Morel, Philippe; Roth, Arnaud; Rubbia-Brandt, Laura; Schiffer, Eduardo; Ris, Frederic; Toso, Christian
• Is Part Of: Expert review of anticancer therapy. Volume 16:Issue 12(2016)
• Page Start: 1277
• Page End: 1290
• Publication Date: 2016-12-01
• Subjects: Colorectal liver metastases -- liver cancer -- liver locoregional treatment -- liver transplantation -- liver surgery; Cancer -- Treatment -- Periodicals; 616.99406
• DOI: 10.1080/14737140.2016.1249855
• Languages: English
• ISSNs: 1473-7140

Abstract

ABSTRACT: Introduction: Colorectal liver metastasis (CRLM) is the most frequent indication for liver resection in many centers. Recent improvements in oncology, surgery, interventional radiology, pathology and anesthesiology allow curative treatment in a larger proportion of patients with CRLM. Areas covered: We illustrate the various aspects of the management of CRLM through 11 questions that summarize the topic, from the current obtained survival to future perspectives such as transplantation. The limits of a curative treatment are also presented from different angles, such as the benefits of pathology, the surgical options for extreme resections, the available chemotherapies and their efficacy, or the non-surgical ablative treatments. Expert commentary: Given the increasing therapeutic possibilities, we strengthen the importance to analyze the situation of each patient with CRLM in a dedicated multidisciplinary team, in order to offer the best individualized treatment combination.