Triplet NOAH supersequences optimised for small molecule structure characterisation. (6th June 2019)

• Record Type: Journal Article
• Authors: Claridge, Tim D.W.; Mayzel, Maksim; Kupče, Ēriks
• Is Part Of: Magnetic resonance in chemistry. Volume 57:Number 11(2019)
• Page Start: 946
• Page End: 952
• Publication Date: 2019-06-06
• Subjects: COSY -- HMBC -- HSQC -- MFA -- NMR -- NOAH -- NOESY -- NUS -- ROESY -- TOCSY; Nuclear magnetic resonance spectroscopy -- Periodicals; Chemistry, Organic -- Periodicals; Magnetic resonance -- Periodicals; 538.36
• DOI: 10.1002/mrc.4887
• Languages: English
• ISSNs: 0749-1581

Abstract

Abstract: A series of NMR supersequences are presented for the time‐efficient structure characterisation of small molecules in the solution state. These triplet sequences provide HMBC, HSQC, and one homonuclear correlation experiment of choice according to the NMR by Ordered Acquisition using 1 H detection principle. The experiments are demonstrated to be compatible with non‐uniform sampling schemes and may be acquired and processed under full automation. Abstract : NOAH NMR supersequences are presented for the time‐efficient structure characterisation of small molecules in the solution state. These triplet sequences provide HMBC, HSQC, and one homonuclear correlation experiment of choice. The experiments are demonstrated to be compatible with non‐uniform sampling schemes and may be acquired and processed under full automation.