Clinical staging of upper urinary tract urothelial carcinoma for T staging: Review and pictorial essay. (4th August 2019)

• Record Type: Journal Article
• Authors: Honda, Yukiko; Nakamura, Yuko; Teishima, Jun; Goto, Keisuke; Higaki, Toru; Narita, Keigo; Akagi, Motonori; Terada, Hiroaki; Kaichi, Yoko; Fujii, Shinsuke; Hayashi, Tetsutaro; Matsubara, Akio; Sentani, Kazuhiro; Yasui, Wataru; Iida, Makoto; Awai, Kazuo
• Is Part Of: International journal of urology. Volume 26:Number 11(2019)
• Page Start: 1024
• Page End: 1032
• Publication Date: 2019-08-04
• Subjects: clinical staging -- computed tomography urography -- magnetic resonance imaging -- upper urinary tract -- urothelial carcinoma; Urology -- Periodicals; Genitourinary organs -- Periodicals; Urologic Diseases -- Periodicals; 616.6005
• DOI: 10.1111/iju.14068
• Languages: English
• ISSNs: 0919-8172

Abstract

Abstract: Upper urinary tract urothelial carcinoma is staged using the TNM classification of malignant tumors. Preoperative TNM is important for treatment planning. Computed tomography urography is now widely used for clinical survey of upper urinary tract carcinoma because of its diagnostic accuracy. Computed tomography urography is recommended as the first‐line imaging procedure in several guidelines. Several reports stated that computed tomography urography is also useful for staging. However, no educational and practical reviews detailing the T staging of upper urinary tract urothelial carcinomas using imaging are available. We discuss the scanning protocol, T staging using computed tomography urography, limitations, magnetic resonance imaging, computed tomography comparison and pitfalls in imaging of upper urinary tract urothelial carcinoma. A recent study reported the high diagnostic accuracy of computed tomography urography with respect to T3 or higher stage tumors. To date, images that show a Tis–T2 stage have not been reported, but various studies are ongoing. Although magnetic resonance imaging has lower spatial resolution than computed tomography urography, magnetic resonance imaging can be carried out without radiation exposure or contrast agents. Magnetic resonance imaging also offers the unique ability of diffusion‐weighted imaging without contrast agent use. Some researchers reported that diffusion‐weighted imaging is useful not only for detecting lesions, but for predicting the T stage and tumor grade. We recommend the appropriate use of computed tomography and magnetic resonance while considering the limitations of each modality and the pitfalls in upper urinary tract urothelial carcinoma imaging.