Characterizing the size of the target region for atraumatic opening of the cochlea through the facial recess. (October 2019)

• Record Type: Journal Article
• Authors: Rau, Thomas S.; Kreul, Diana; Lexow, Jakob; Hügl, Silke; Zuniga, M. Geraldine; Lenarz, Thomas; Majdani, Omid
• Is Part Of: Computerized medical imaging and graphics. Volume 77(2019)
• Publication Date: 2019-10
• Subjects: Targeting accuracy -- Cochlear implant -- Cochleostomy -- Insertion vector -- Minimally invasive -- Image-Guided surgery; Diagnostic imaging -- Periodicals; Imaging systems in medicine -- Periodicals; Diagnosis, Radioscopic -- Data processing -- Periodicals; Diagnostic Imaging -- Periodicals; Imagerie pour le diagnostic -- Périodiques; Diagnostic imaging; Periodicals; Electronic journals; Electronic journals; 616.0754
• DOI: 10.1016/j.compmedimag.2019.101655
• Languages: English
• ISSNs: 0895-6111

Abstract

Graphical abstract: Highlights: image-processing software for analysing the cochlear hook region was developed. first measure for the size of the valid target region using 3D histological data of multiple temporal bone specimens. cochlea opening is safely possible within a region of ∅ 1.56 mm ± 0.10 mm accuracy for hearing preservation surgery needs to be ≤ 0.3mm. anatomical 3D models depict the complexity of the cochlear hook region. Abstract: Surgical treatment with a cochlear implant (CI) for hearing rehabilitation requires a highly accurate and personalized opening of the inner ear (cochlea) to protect the delicate intra-cochlear fine structures, whose functional integrity needs to be maintained to preserve residual hearing. Spatial orientation within the complex anatomy of the lateral skull base during the procedure is a highly demanding task for the surgeon. In order to reduce risk of facial nerve palsy and loss of residual hearing as well as to establish minimally invasive CI surgery (minCIS), image-guided procedures incorporating surgical assistance systems are under development. However, there is a lack of an accuracy threshold value or range that such a system needs to fulfill to be considered sufficiently accurate for atraumatic opening of the inner ear. In this study, high resolution three-dimensional (3D) morphological images of eight human temporal bone specimens were manually segmented to build anatomical models of the human inner ear including all surgically relevant intra-cochlear structures as well as the facial recess. These 3D models were used to plan the surgical access path to the basal turn of the cochlea using the mastoidectomy posterior tympanotomy approach (MPTA). Therefore, custom-made image-processing software was developed to perform both path planning and identification of the valid target region— i.e., the largest possible region for atraumatic opening of the scala tympani. The developed 3D models provide visualization of the complex and variable anatomy of the basal portion of the human cochlear duct (also known as cochlear "hook region") as well as its spatial relationship to the facial recess. Their spatial arrangement directly impacts the accessibility of the hook region and limits the entry direction into scala tympani. The average diameter of the target region was found to be 1.56 mm ± 0.10 mm (range: 1.43 to 1.72 mm). The anatomic variability and the need for a high safety level of at least 95% for hearing preservation CI surgery lead to a remaining safety margin of approximately 0.3 mm. In the future, this accuracy threshold value can serve as benchmark during the pre-clinical evaluation of image-guidance technologies to allow for highly accurate CI surgery.