Recent trends in the synthesis of 1, 2, 3-thiadiazoles. (2nd December 2019)

• Record Type: Journal Article
• Authors: Irfan, Ali; Batool, Fozia; Ahmad, Sajjad; Ullah, Riaz; Sultan, Aeysha; Sattar, Rabia; Nisar, Bushra; Rubab, Laila
• Is Part Of: Phosphorus, sulfur, and silicon and the related elements. Volume 194:Number 12(2019)
• Page Start: 1098
• Page End: 1115
• Publication Date: 2019-12-02
• Subjects: 1, 2, 3-Thiadiazole derivatives -- one-pot-synthesis -- cyclization -- triazole -- pyrazole; Sulfur compounds -- Periodicals; Organosulfur compounds -- Periodicals; Phosphorus compounds -- Periodicals; Organophosphorus compounds -- Periodicals; Silicon compounds -- Periodicals; Organosilicon compounds -- Periodicals; 546
• DOI: 10.1080/10426507.2019.1633323
• Languages: English
• ISSNs: 1042-6507

Abstract

Abstract: 1, 2, 3-Thiadiazoles, structurally active pharmacophores have attracted significant attention of synthetic chemists, medicinal and pharmaceutical researchers because of their versatile biological activities against various diseases such as herbicidal, insecticidal, antiviral, antitumor, antimicrobial, anticancer, plants activator and anti-amoebic activities. A literature survey of the last decade presented in this review article summarizes the major synthetic approaches, methodologies and strategies adopted for the synthesis of 1, 2, 3-thiadiazole scaffolds which will be help for medicinal chemists and pharmacists in future synthesis and development of novel therapeutic agents. Graphical Abstract: