Multi-level collagen aggregates and their applications in biomedical applications. Issue 8 (17th November 2019)

• Record Type: Journal Article
• Authors: Dan, Weihua; Chen, Yining; Dan, Nianhua; Zheng, Xin; Wang, Lu; Yang, Changkai; Huang, Yanping; Liu, Xinhua; Hu, Yang
• Is Part Of: International journal of polymer analysis and characterization. Volume 24:Issue 8(2019)
• Page Start: 667
• Page End: 683
• Publication Date: 2019-11-17
• Subjects: Collagen -- collagen fibers -- collagen aggregates -- collagen modification and application; Polymers -- Analysis -- Periodicals; 547.705
• DOI: 10.1080/1023666X.2019.1656387
• Languages: English
• ISSNs: 1023-666X

Abstract

Abstract: In this review, the system of multi-level collagen aggregates including collagen molecular, collagen fiber, advanced collagen aggregates, and tissues was reviewed. The preparation methods of multi-level collagen aggregates were introduced, and the relationship between structure and properties of them was analyzed and clarified. The general rule of structure-activity relationship of multi-level collagen aggregates under different modifiers and modified conditions was analyzed, and a theoretical basis for the application of multi-level collagen aggregates in biomedical field was provided. Finally, the applications of a series of biomedical materials of multi-level collagen aggregates and their modified products were listed. It is confirmed that the application field of multi-level collagen aggregates and their modified products might be far greater than collagen and other biomass. The multi-level collagen aggregates might have a very broad application prospect.