Perspectives on Scedosporium species and Lomentospora prolificans in lung transplantation: Results of an international practice survey from ESCMID fungal infection study group and study group for infections in compromised hosts, and European Confederation of Medical Mycology. Issue 5 (22nd July 2019)

• Record Type: Journal Article
• Authors: Rammaert, Blandine; Puyade, Mathieu; Cornely, Oliver A.; Seidel, Danila; Grossi, Paolo; Husain, Shahid; Picard, Clément; Lass‐Flörl, Cornelia; Manuel, Oriol; Le Pavec, Jérôme; Lortholary, Olivier
• Other Names: Nagel Claudia investigator.; Westall Glen investigator.; Morrissey Orla investigator.; Chambers Daniel investigator.; Eschertzhuber Stephan investigator.; Coussement Julien investigator.; Knoop Christiane investigator.; Vos Robin investigator.; Dupont Lieven investigator.; Dumonceaux Michel investigator.; Campos Silvia Vidal investigator.; Kabbani Dima investigator.; Cervera Carlos investigator.; Luong Me‐Linh investigator.; Blanchard Elodie investigator.; Sénéchal Agathe investigator.; Pavec Jérôme Le investigator.; Brugière Olivier investigator.; Boussaud Veronique investigator.; Guillemain Romain investigator.; Bervar Jean‐Francois investigator.; Claustre Johanna investigator.; Haloun Alain investigator.; Hirschi Sandrine investigator.; Reynaud Martine investigator.; Picard Clément investigator.; Kneidinger Nikolaus investigator.; Gottlieb Jens investigator.; Roilides Emmanuel investigator.; Zarrinfar Hossein investigator.; Rosso Lorenzo investigator.; Morlacchi Letizia Corinna investigator.; Dell'Amore Andrea investigator.; Loy Monica investigator.; Santos Claudy Oliveira dos investigator.; Rello Jordi investigator.; Monforte Victor investigator.; Martin‐Gomez Maria Teresa investigator.; Medrano Francisco López investigator.; Fernández‐Ruiz Mario investigator.; Sole Amparo investigator.; Cifrian Jose M. investigator.; Neofytos Dionysios investigator.; Mueller Nicolas investigator.; Benden Christian investigator.; Brill Anne Kathrin investigator.; Kiyan Esen investigator.; Gould Kate investigator.; Gkrania‐Klotsas Effrossyni investigator.; David Miruna investigator.; Weigt Sam investigator.; Kwak Eun Jeong investigator.; Silveira Fernanda investigator.; Hadjiliadis Denis investigator.; Baddley John investigator.; Danziger‐Isakov Lara investigator.; Bhorade Sangeeta investigator.; Ison Michael investigator.; Wolfe Cameron investigator.; Aslam Saima investigator.; Budem Marie investigator.; Musetti Ana investigator.;
• Is Part Of: Transplant infectious disease. Volume 21:Issue 5(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-07-22
• Subjects: invasive fungal disease -- lomentosporiosis -- scedosporiosis -- solid organ transplantation; Transplantation of organs, tissues, etc -- Complications -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 617.01
• DOI: 10.1111/tid.13141
• Languages: English
• ISSNs: 1398-2273

Abstract

Abstract: Background: Scedosporium species and Lomentospora prolificans (S/L) are the second most common causes of invasive mold infections following Aspergillus in lung transplant recipients. Methods: We assessed the current practices on management of S/L colonization/infection of the lower respiratory tract before and after lung transplantation in a large number of lung transplant centers through an international practice survey from October 2016 to March 2017. Results: A total of 51 respondents from 45 lung transplant centers (17 countries, 4 continents) answered the survey (response rate 58%). S/L colonization was estimated to be detected in candidates by 48% of centers. Only 18% of the centers used a specific medium to detect S/L colonization. Scedosporium spp. colonization was a contraindication to transplantation in 10% of centers whereas L prolificans was a contraindication in 31%; 22% of centers declared having had 1‐5 recipients infected with S/L in the past 5 years. Conclusions: This survey gives an overview of the current practices regarding S/L colonization and infection in lung transplant centers worldwide and underscores the need of S/L culture procedure standardization before implementing prospective studies.