Antlion (Myrmeleon sp.) Infusion as Antidiabetic in Dexamethasone Induced Mice. (July 2019)

• Record Type: Journal Article
• Authors: Maryati, Y; Alifiar, I; Nurfatwa, M; Nofianti, T; Rahayuningsih, N
• Is Part Of: Journal of physics. Volume 1179(2019)
• Publication Date: 2019-07
• Subjects: Physics -- Congresses; 530.5
• DOI: 10.1088/1742-6596/1179/1/012177
• Languages: English
• ISSNs: 1742-6588

Abstract

Abstract: Diabetes Mellitus (DM) is a degenerative disease which classified as number 6 death caused worldwide mark by hyperglycemia condition. Antlion ( Myrmeleon sp .) used as antidiabetic traditionally in Tasikmalaya. This research aims to evaluate antlion ( Myrmeleon sp .) infusion antidiabetic activity. Dexamethasone was used to induce hyperglycemia condition in all treatment group. Negative group were given CMC 0, 5%, positive group were given metformin 1, 3 mg/20 g bw, dose 1, dose 2 and dose 3 were given antlion infusion 0, 104 mg/20 g bw, 0, 208 mg/20 g bw and 0, 416 mg/20 g bw respectively. The effect of antlion infusion was observed at 0, 30, 60, 90 and 120 minutes. Antlion infusion has an antidiabetic activity which dose 2 showed the best effect in decreasing blood glucose. The best blood glucose decreasement (BGC) come out from dose 2 with % BGC at 60, 90 and 120 minutes 28, 19%, 28, 39 %, and 31, 20 % respectively.