Advances of Wnt signalling pathway in dental development and potential clinical application. (2nd October 2019)

• Record Type: Journal Article
• Authors: Lu, Xi; Yang, Jun; Zhao, Shouliang; Liu, Shangfeng
• Is Part Of: Organogenesis. Volume 15:Number 4(2019)
• Page Start: 101
• Page End: 110
• Publication Date: 2019-10-02
• Subjects: crown morphogenesis -- Dentin regeneration -- root formation -- Wnt signalling; Morphogenesis -- Periodicals; Morphogenesis; Periodicals; Electronic journals; 571.53
• DOI: 10.1080/15476278.2019.1656996
• Languages: English
• ISSNs: 1547-6278

Abstract

ABSTRACT: Wnt signalling pathway is widely studied in many processes of biological development, like embryogenesis, tissue homeostasis and wound repair. It is universally known that Wnt signalling pathway plays an important role in tooth development. Here, we summarized the function of Wnt signalling pathway during tooth initiation, crown morphogenesis, root formation, and discussed the therapeutic potential of Wnt modulators.